July 2024
Put Resmetirom in Perspective for NASH Treatment
Resmetirom (Rezdiffra) will be the first med approved for treatment of nonalcoholic steatohepatitis (NASH) with fibrosis in adults. Our Letter articles provide guidance about this new treatment for certain patients with NASH. Our article clarifies the effectiveness and safety of resmetirom. We also give advice about the place in therapy for this new medication and point out pertinent drug interactions. Our chart, Drug Interactions: Cytochrome P450 (CYP), P-glycoprotein, and More, helps readers sort through other interactions with resmetirom.
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Community Topic: Provide Answers About GLP-1 Agonists for Weight Loss
High demand and persistent shortages are leading to questions about the weight loss meds semaglutide (Wegovy) and tirzepatide (Zepbound). Our Letter articles answer frequently asked questions about GLP-1 agonist medications used for weight loss. We provide recommendations on how to switch between GLP-agonists. Our article also gives guidance about compounded products and clarifies whether patients will need to use a GLP-1 agonist long-term. Our chart, Weight Loss Products, compares GLP-1 agonists and other FDA approved products for weight loss.
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Hospital Pharmacy: Be Alert for Rising Rates of Bacterial Meningitis
A recent CDC health advisory warns about the highest number of bacterial meningitis cases in nearly 10 years. Our article provides guidance on antibiotic selection, with considerations based on patient age and risk factors. We also discuss alternative antibiotic options to consider in times of drug shortages and the controversy over whether patients with meningitis should be treated with steroids and provides guidance on how to individualize the decision. Our resource, Managing Beta-Lactam Allergies, provides guidance on cross-reactivity when patients have a true, severe allergy.
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Supplements for fertility is a growing segment in the dietary supplement market. PCOS is a leading cause for infertility. Inositol is often recommended for PCOS. Our NatMed article discusses the available evidence on using inositol for PCOS. We explain that inositol might offer some benefits for patients with PCOS. But we encourage providers to manage expectations about its effects on fertility – there’s no strong evidence that it improves the chance of getting pregnant.
Supplements for fertility is a growing segment in the dietary supplement market. PCOS is a leading cause for infertility. Inositol is often recommended for PCOS. Our NatMed article discusses the available evidence on using inositol for PCOS. We explain that inositol might offer some benefits for patients with PCOS. But we encourage providers to manage expectations about its effects on fertility – there’s no strong evidence that it improves the chance of getting pregnant.
We have a packed tradeshow schedule this year and would love to meet with you in person! Send us a meeting request if you’ll be attending any of these shows!
Check out where we’ll be in the coming months:
Tasha Jackson, B.S., PharmD, BCSCP, and editor at CriticalPoint, recently posted a blog emphasizing the importance of enforcing staff hygiene, proper garbing, and addressing recent tattoos in hospital pharmacies to maintain a sterile environment. She explains that USP Chapter 797 mandates personnel with recent tattoos to report them to the designated person (DP), who then determines their role in compounding activities during the healing process. It’s noted that effective standard operating procedures (SOPs) are crucial for managing staff restrictions and alternate duties to minimize contamination risk. Additionally, thorough documentation and staff education on hygiene and contamination risks are essential for compliance and maintaining a safe compounding environment.
Tasha Jackson, B.S., PharmD, BCSCP, and editor at CriticalPoint, recently posted a blog emphasizing the importance of enforcing staff hygiene, proper garbing, and addressing recent tattoos in hospital pharmacies to maintain a sterile environment. She explains that USP Chapter 797 mandates personnel with recent tattoos to report them to the designated person (DP), who then determines their role in compounding activities during the healing process. It’s noted that effective standard operating procedures (SOPs) are crucial for managing staff restrictions and alternate duties to minimize contamination risk. Additionally, thorough documentation and staff education on hygiene and contamination risks are essential for compliance and maintaining a safe compounding environment.
Following the conclusion of the 2024 legislative session, Bula’s policy analysts are preparing a comprehensive summary highlighting significant legislative changes across each jurisdiction. Here are updates from three states that have recently passed legislation that expanded the scope of practice for pharmacists, technicians, and interns:
Michigan
Oregon
Tennessee
For more information on the latest changes from the 2024 legislative session and to learn how Bula can support your organization’s needs, contact us today.
As we recognize Herbal/Prescription Interaction Awareness Month, now is the perfect time to ensure your pharmacists are able to properly care for and counsel patients on natural medicines and supplements. RxAdvanced: Guide to Natural Medicines is an advanced, 11-hour ACPE-accredited CE training program that equips pharmacists with a foundational understanding of natural medicines, enabling them to make safe and effective recommendations, prevent drug interactions and adverse events, and educate patients and other healthcare team members. Additionally, NatMed Pro is a must-have tool for your pharmacy team, as it’s the largest and most trusted, evidence-based natural medicines database designed to improve clinical understanding of integrative medicine, natural therapies, and dietary and herbal supplements.
In this webinar, our Solutions Executive, Keith Marston, provides an in-depth overview and walkthrough of our exclusive CE/CME & Training Organizer and Learning Management Portal. He covers what you’ll get with our CE/CME & Training Organizer and Learning Management Portal, including comprehensive CE and training management, nationwide tracking and reporting, streamlined communication and documentation, and a user-friendly, integrated platform.
Check out this month’s podcast, Pharmacotherapy for Anxiety and Depression, and listen in as our expert panel discusses pharmacotherapy for managing generalized anxiety disorder and major depression, with a focus on tailoring first- or second-line options to individual patient needs.
Pharmacist’s Letter and Prescriber Insights subscribers can get CE credit for listening to our podcasts.